Kisspeptin-10

Kisspeptin-10 is a decapeptide — a chain of ten amino acids — with the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂. It is the shortest bioactive fragment of the kisspeptin-54 protein, which is encoded by the KISS1 gene, first identified in 1996 at Pennsylvania State University. The peptide has the molecular formula C₆₃H₈₃N₁₇O₁₄, a molecular weight of 1302.45 g/mol, and CAS number 374675-21-5. The C-terminal amide group on the final phenylalanine is a defining structural feature that distinguishes it from truncated kisspeptin variants. Supplied as a white lyophilized powder with purity of 98% or higher by HPLC, highly soluble in bacteriostatic water. Store refrigerated at 2–8 °C.